Globomycin 31675 C2H4O2/c1-32(2)23-36(66)54(95)76-37(14-17-51(91)92)57(98)77-38(15-18-52(93)94)58(99)80-42(30-83)56(97)72-26-47(87)69-25-46(86)70-28-49(89)74-41(24-33(3)4)59(100)81-53(34(5)6)62(103)79-40(13-16-45(67)85)63(104)82-21-10-12-44(82)61(102)73-27-48(88)71-29-50(90)75-43(31-84)60(101)78-39(19-22-107-7)55(96)68-20-9-8-11-35(65)64(105)106

C2H4O2/c1-32(2)23-36(66)54(95)76-37(14-17-51(91)92)57(98)77-38(15-18-52(93)94)58(99)80-42(30-83)56(97)72-26-47(87)69-25-46(86)70-28-49(89)74-41(24-33(3)4)59(100)81-53(34(5)6)62(103)79-40(13-16-45(67)85)63(104)82-21-10-12-44(82)61(102)73-27-48(88)71-29-50(90)75-43(31-84)60(101)78-39(19-22-107-7)55(96)68-20-9-8-11-35(65)64(105)106

Angoline is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11

InChi: InChI=1S/C29H40N2O3/c1-29-16-15-23-22-10-8-21(34-2)19-20(22)7-9-24(23)25(29)11-12-26(29)30-17-5-3-4-6-18-31-27(32)13-14-28(31)33/h8

6R)-3-amino-5-{[(2S

4)5)74-50(83)41(23-32-14-16-35(79)17-15-32)70-53(86)44(28-78)73-51(84)42(24-33-26-65-37-11-7-6-10-36(33)37)71-52(85)43(25-34-27-63-30-66-34)72-48(81)38-18-19-47(80)67-38/h6-7

Globomycin 31675 C2H4O2/c1-32(2)23-36(66)54(95)76-37(14-17-51(91)92)57(98)77-38(15-18-52(93)94)58(99)80-42(30-83)56(97)72-26-47(87)69-25-46(86)70-28-49(89)74-41(24-33(3)4)59(100)81-53(34(5)6)62(103)79-40(13-16-45(67)85)63(104)82-21-10-12-44(82)61(102)73-27-48(88)71-29-50(90)75-43(31-84)60(101)78-39(19-22-107-7)55(96)68-20-9-8-11-35(65)64(105)106Globomycin is a lipopeptide antibiotic and a signal peptidase II (LspA) inhibitor. Globomycin inhibits processing of the prolipoprotein by binding irreversibly to the peptidase. Globomycin has toxic for the mollicute Spiroplasma melliferum with a MIC in the range 6. 25 12. 5 M. Product information CAS Number: 67076 74 8 Molecular Weight: 655. 82 Formula: C32H57N5O9 Chemical Name: 12 butan 2 yl 19 hexyl 6 (1 hydroxyethyl) 9 (hydroxymethyl) 16, 18