CY-09 G11-azide 4-d]pyrimidin-4-yl)piperazine-1-carboxylate

4-d]pyrimidin-4-yl)piperazine-1-carboxylate

Epub 2015 Jul 6

but weakly inhibited the growth of EGFR-overexpressing tumor xenografts

The novel JAK inhibitor AZD1480 blocks STAT3 and FGFR3 signaling

33-decaoxo-28

CY-09 G11-azide 4-d]pyrimidin-4-yl)piperazine-1-carboxylateCY 09 is a selective and direct NLRP3 inhibitor. CY 09 directly binds to the ATP binding motif of NLRP3 NACHT domain and inhibits NLRP3 ATPase activity, resulting in the suppression of NLRP3 inflammasome assembly and activation. Product information CAS Number: 1073612 91 5 Molecular Weight: 423. 43 Formula: C19H12F3NO3S2 Chemical Name: 4 {[(5Z) 4 oxo 2 sulfanylidene 3 {[3 (trifluoromethyl)phenyl]methyl} 1,3 thiazolidin 5 ylidene]methyl}benzoic acid