But as I said earlier, Infect is anything but fair, which means they are ready and waiting for your fair removal like Decay and Path to Exile
Some monsters (such as "Elemental HERO Rampart Blaster" and the "Superheavy Samurai" monsters) may attack in face-up Defense Position
Aquitects Will, Phantasmal Terrain, Dream Thrush, Grixis Illusionist, Opposition, Parallax Tide, Reef Shaman, Seas Claim, and Spreading Seas are among the cards that can either change an opponents land into a useless land type, or just get rid of lands for an extended period of time
Shadowspear Indestructible or hexproof are really annoying keywords to deal with if enemy creatures happen to have them
Why not just Solitude/Ephemerate and get a five-mana creature for one-mana, and take two of your opponents creatures along with it