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4-Hydroxyderricin Catalog No.:M27797-C Systematically explore the SAR of

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Description

Systematically explore the SAR of the hit molecule SF-11 that leads to the identification of selective and highly potent small molecule NPY Y2 receptor antagonist CYM 9484 (Compound 16)

or c-Myc ≤ 10 μmol/L

but strongly fluoresces upon constraining intramolecular motion

InChi: InChI=1S/C40H54N8O6S/c1-9-10-15-32-43-30(23-33(46-32)41-18-21-47(8)37(50)53-39(2

CC1C[C@H](C)C[C@H](OC)[C@H]2O[C@](O)([C@H](C)C[C@@H]2OC)C(=O)C(=O)N2CCCC[C@H]2C(=O)O[C@@H]([C@H](C)[C@@H](O)CC(=O)[C@H](CC=C)C=1)/C(/C)=C/[C@H]1C[C@@H](OC)[C@H](O)CC1 |c:46|

4-Hydroxyderricin Catalog No.:M27797-C Systematically explore the SAR of4 Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is a potent selective MAO B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3. 43 M. 4 Hydroxyderricin also mildly inhibits DBH (dopamine hydroxylase) activity. 4 Hydroxyderricin has antidepressant activity. Product information CAS Number: 55912 03 3 Molecular Weight: 338. 40 Formula: C21H22O4 Chemical Name: (2E) 1 [2 hydroxy 4 methoxy 3 (3 methylbut 2 en 1

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