PXS-5153A monohydrochloride 5041 Leuk Lymphoma

Leuk Lymphoma

shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR

Smiles: COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)/C(=C/C)/[C@@H]1CC(=O)OCCC1C=C(O)C(O)=CC=1

Smiles: OC(=O)C1=CC(=O)C=C(O1)C(O)=O

4 for AR wild type and AR mutation T877A

PXS-5153A monohydrochloride 5041 Leuk LymphomaPXS 5153A monohydrochloride is a potent, selective, orally active and fast acting lysyl oxidase like 2 3 enzymatic (LOXL2 LOXL3) inhibitor, with an IC50 of <40 nM for LOXL2 across all mammalian species and an IC50 of 63 nM for human LOXL3. PXS 5153A monohydrochloride could reduce crosslinks and ameliorates fibrosis. Product information Molecular Weight: 438. 95 Formula: C20H24ClFN4O2S Chemical Name: 3 {1 [(2Z) 4 amino 2 fluorobut 2 en 1 yl] 2 methyl