PIK-III - CAS# 1383716-40-2 6053 5-10 µM final concentration in

5-10 µM final concentration in various in vitro assays

74(15):4170-82

Pharmacokinetics of Ceftaroline in Normal Body Weight and Obese (Classes I

Rupaimoole R

InChiKey: MBOMYENWWXQSNW-AWEZNQCLSA-N

PIK-III - CAS# 1383716-40-2 6053 5-10 µM final concentration inPIK III, also known as VPS34 IN2, CAS No. 1383716 40 2, is a VPS34 inhibitor which blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. PIK III binds a unique hydrophobic pocket not present in related kinases such as PI(3)K. PIK III acutely inhibits autophagy and de novo lipidation of LC3, and leads to the stabilization of autophagy substrates. . Product information CAS Number: 1383716 40 2 Molecular