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Ku-55933 - CAS# 587871-26-9 0193 p300 and CBP are transcriptional

SKU: 858224767

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Description

p300 and CBP are transcriptional co-activators that modulate DNA replication

Arrendale RF

49 mg/mL in EtOH with ultrasonic

is a specific inhibitor of the Ca(2+)/calmodulin-dependent protein kinase kinase

orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer

Ku-55933 - CAS# 587871-26-9 0193 p300 and CBP are transcriptionalKU 55933, CAS No. 587871 26 9, is an ATM inhibitor. KU 55933 blocks the phosphorylation of Akt induced by insulin and insulin like growth factor I in cancer cells that exhibit abnormal Akt activity. Moreover, KU 55933 inhibits cancer cell proliferation by inducing G(1) cell cycle arrest. It does so through the downregulation of the synthesis of cyclin D1, a protein known to be elevated in a variety of tumors. In addition, KU 55933 treatment during

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