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Smiles: O=S(=O)(C1=CC=CC2=CC=CC=C21)N1C=CC2=CC=C(C=C12)N1CC2CCCN2CC1
PubMed PMID: 30401637
Smiles: CC(C)C(=O)O[C@H]1[C@@H](OC(=O)C(C)C)[C@@H](O[C@@]1(COC(=O)C(C)C)N=[N+]=[N-])N1C=CC(N)=NC1=O
Purvalanol A induced a strong G2-M arrest
12-tetraoxapentadecan-15-amido)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoate
AL 8810 isopropyl ester pyl Smiles: O=S(=O)(C1=CC=CC2=CC=CC=C21)N1C=CC2=CC=C(C=C12)N1CC2CCCN2CC1EC50: 430 nM AL 8810 is a a FP receptor antagonist. Prostaglandin F receptor (FP), a receptor belonging to the prostaglandin (PG) group of receptors, binds to and mediates the biological actions of Prostaglandin F2 (PGF2). In vitro: Previous study found that AL 8810 had weak agonist potency in A7r5 cells and 3T3 fibroblasts. AL 8810 exhibited properties of an apparent competitive antagonist, which was demonstrated by producing parallel dextral shifts