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HDAC2 (IC50 ~0
Okada-Iwabu
AMI-1 can modulate nuclear receptor-regulated transcription from estrogen and androgen response elements
including anti-proliferative effects in cancer cells
for cellular assays and in vivo use
GSK2879552 dihydrochloride - LSD1 Inhibitor. CAS# 1902123-72-1 size:10mg solid HDAC2 (IC50 ~0GSK2879552 dihydrochloride, CAS No. 1902123 72 1, is a highly potent, selective and orally bioavailable irreversible inhibitor of Lysine Specific Demethylase 1 (LSD1). It is highly selective over related enzymes such as MAO A B. A proliferation screen of cell lines representing a number of tumor types indicated that small cell lung carcinoma (SCLC) is sensitive to GSK2879552s inhibition. It increases H3K4 methylation selectively at genomic regions
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