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12682-12687
Plasma drug concentrations peak rapidly after oral administration of doses between 25-100 mg/kg (Tmax=0
BMS-986121 is built on a chemical scaffold representing a new chemotype for μ receptor PAMs
01-1 μM) inhibits the direct phosphorylation of Tau by DYRK1A EHT 5372 reduces Aβ production in a dose-dependent reduction with an IC50 of 1
RPMI-8226 and NCI-H929 cells
LY-311727 Size:Contact [email protected] for quotation 12682-12687LY 311727 is a potent secretory non pancreatic phospholipase A2 (sPLA2) inhibitor (IC50 <1 M for group IIA sPLA2). sPLA2 is an important proinflammatory enzyme. Product information CAS Number: 164083 84 5 Molecular Weight: 430. 43 Formula: C22H27N2O5P Chemical Name: (3 {[1 benzyl 3 (carbamoylmethyl) 2 ethyl 1H indol 5 yl]oxy}propyl)phosphonic acid Smiles: CCC1=C(CC(N)=O)C2=CC(=CC=C2N1CC1C=CC=CC=1)OCCCP(O)(O)=O InChiKey: OPWQYOUZRHDKBR UHFFFAOYSA N
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