CDK2 and CDK5
PHA-665752 also significantly blocks HGF- and c-Met-dependent functions such as cell motility and cell proliferation with IC50 of 40-50 nM and 18-42 nM
BAY-1797 exerts no measurable activity on hERG and carbonic anhydrase II (both IC50>10 μM)
Smiles: CC(C)(O)[C@H](O)CC1=CC2C=CC(=O)OC=2C=C1O
4 hours) leads to proteasome dysfunction and ER stress
N-Methylnuciferine xy-2-sulfoamino-D-glucose sodium CDK2 and CDK5N Methylnuciferine, an alkaloid from Lotus Plumule, ameliorate lipopolysaccharide induced depression like behavior. Product information CAS Number: 754919 24 9 Molecular Weight: 310. 41 Formula: C20H24NO2 Chemical Name: (9R) 15,16 dimethoxy 10,10 dimethyl 10 azatetracyclo[7. 7. 1. 0,. 0,]heptadeca 1(16),2,4,6,13(17),14 hexaen 10 ium Smiles: COC1=CC2CC[N+](C)(C)[C@@H]3CC4=CC=CC=C4C(C=23)=C1OC InChiKey: NJSAZXBJMATEKS MRXNPFEDSA N InChi: InChI=1S