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Laurent MA
J Chromatogr B Biomed Sci Appl
IMB-301 binds to hA3G
and potently inhibits IRE1α RNase activity against XBP1 and Ins2 RNAs
InChi: InChI=1S/C40H49N7O7/c41-22-8-7-14-31(38(52)46-32(37(42)51)24-28-12-5-2-6-13-28)44-36(50)26-43-39(53)34-15-9-23-47(34)40(54)33(25-29-16-19-30(48)20-17-29)45-35(49)21-18-27-10-3-1-4-11-27/h1-6
TPh A TI-277 Laurent MATPh A (Triphenyl Compound A) is a potent inhibitor of the nuclear protein pirin and binds specifically to pirin with a Ki of 0. 6 uM. TPh A disrupts the formation of the bcl3pirin complex. TPh A can be used as a novel small molecule tool to regulate pirin in cells. Product information CAS Number: 21306 65 0 Molecular Weight: 399. 53 Formula: C21H21NO3S2 Chemical Name: N {[4 (benzyloxy)phenyl](methyl) sulfanylidene} 4 methylbenzene 1 sulfonamide
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