Pay in 4 interest-free payments of $25.00 Learn more
Ships within 48 hours · Estimated delivery Jul 27 - Aug 1
PubMed PMID: 26033479
InChiKey: QZRSNVSQLGRAID-UHFFFAOYSA-N
59(4-5):268-75
InChiKey: GVWIWZFXCGTSLL-RDAQQDRPSA-N
2014 Mar 18
17-AAG Hydrochloride zithromycin PubMed PMID: 2603347917 AAG hydrochloride is a potent HSP90 inhibitor with IC50 value of 5 nM, which is a 100 fold higher binding affinity for HSP90 derived from tumour cells than that from normal cells. It is less toxic by binding to Hsp90 and altering its function. It causes the degradation of HER2, HER3, Akt, and both mutant and wild type androgen receptor (AR), leading to the RB dependent G1 growth arrest of prostate cancer cells. It has the ability to induce
US$ 90.00
US$ 19.95
US$ 100.00
US$ 85.00
US$ 21.95
US$ 19.95
US$ 14.99