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Bafetinib analog, Lyn-IN-1 - CAS# 887650-05-7 clozanide 365(18):1735-7

SKU: 48383022169

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Description

365(18):1735-7

Molecular Weight: 197

Cardamonin is a modulator of STAT3 activation in prostate cancer

KN-93 phosphate

Pulsatilla saponin D (SB365)

Bafetinib analog, Lyn-IN-1 - CAS# 887650-05-7 clozanide 365(18):1735-7Bafetinib, also known as INNO 406 and NS187, is an orally bioavailable 2 phenylaminopyrimidine derivative with potential antineoplastic activity. Bafetinib specifically binds to and inhibits the Bcr Abl fusion protein tyrosine kinase, an abnormal enzyme produced by Philadelphia chromosomal translocation associated with chronic myeloid leukemia (CML). This agent also inhibits the Src family member Lyn tyrosine kinase, upregulated in imatinib resistant

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