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Local delivery of novel MRTF/SRFinhibitors prevents scar tissue formation in a preclinical model of fibrosis
serum hydroxyproline (HOP) levels
GSK650394 inhibits SGK1-mediated epithelial transport with an IC50 of 0
DMH-1 (5 μM and 10 μM) inhibits CDDP-induced autophagy in HeLa cells and enhances the ability of CDDP to reduce HeLa cell viability
CAS Number: 951131-15-0
PI-103 butyric acid (4-PBA) Local delivery of novel MRTF/SRFinhibitorsPI 103 is a potent, cell permeable, ATP competitive inhibitor of phosphatidylinositol 3 kinase (PI3K) family members with selectivity toward DNA PK, PI3K (p110), and mTOR. Product information CAS Number: 371935 74 9 Molecular Weight: 348. 36 Formula: C19H16N4O3 Synonym: PI103 PI 103 Chemical Name: 3 (4 morpholinopyrido[3',2': 4,5]furo[3,2 d]pyrimidin 2 yl)phenol Smiles: OC1C=C(C=CC=1)C1=NC2=C(OC3=NC=CC=C23)C(=N1)N1CCOCC1 InChiKey: TUVCWJQQGGETHL