DMT1 blocker 1 yl 2-(2-(((benzyloxy)carbonyl)amino)propan-2-yl)-5-hydroxy-1-methyl-6-oxo-1 6-dihydropyrimidine-4-carboxylate-d3 orally active and non-competitive kainate-

orally active and non-competitive kainate- and AMPA-activated currents antagonist with IC50s of 7

CaCCinh-A01 (TMEM16 Blocker I) is a blocker of TMEM16A with IC50 of 2

SB-200646A (20 mg/kg

Smiles: CC(C)=CCC1(C(=C(O)C2=CC=CC=C2C1=O)C(=O)OC)C1=CC(=O)C2=CC=CC=C2C1=O

Enhancement of proteasome activity through inhibition of Usp14 may offer a strategy to reduce the levels of aberrant proteins in cells under proteotoxic stress

DMT1 blocker 1 yl 2-(2-(((benzyloxy)carbonyl)amino)propan-2-yl)-5-hydroxy-1-methyl-6-oxo-1 6-dihydropyrimidine-4-carboxylate-d3 orally active and non-competitive kainate-DMT1 blocker 1 is a blocker of divalent metal transporter 1 (DMT1) with an IC50 of 0. 64 M, is expected to block iron uptake by enterocytes in vivo. Product information CAS Number: 1354790 56 9 Molecular Weight: 294. 31 Formula: C16H14N4O2 Chemical Name: 5 methyl 3 oxo N phenyl 2 (pyridin 2 yl) 2,3 dihydro 1H pyrazole 4 carboxamide Smiles: CC1NN(C2=CC=CC=N2)C(=O)C=1C(=O)NC1C=CC=CC=1 InChiKey: QJEBTCLOCMTSJU UHFFFAOYSA N InChi: InChI=1S C16H14N4O2 c1