N-Desethyl Sunitinib Size:Solid 10 mg Dmitrovsky E

Dmitrovsky E

Atipamezole alters the behavioural effects of pramipexole and increases pramipexole concentration in blood plasma

Smiles: NS(=O)(=O)NC1=NC=NC(OCCOC2N=CC(Br)=CN=2)=C1C1C=CC(Br)=CC=1

and pityriasis versicolor) and shampoos (used primarily to treat dandruff—seborrhoeic dermatitis of the scalp)

CAS Number: 346640-08-2

N-Desethyl Sunitinib Size:Solid 10 mg Dmitrovsky EN Desethyl Sunitinib is a metabolite of sunitinib. Sunitinib is a potent, ATP competitive VEGFR, PDGFR and KIT inhibitor with Ki values of 2, 9, 17, 8 and 4 nM for VEGFR 1, 2, 3, PDGFR and KIT, respectively. Sunitinib also potently inhibits Kit and FLT 3. Sunitinib inhibits VEGF induced proliferation of serum starved HUVECs with IC50 of 40 nM, and inhibits PDGF induced proliferation of NIH 3T3 cells overexpressing PDGFR or PDGFR with IC50 of 39 nM and