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BAY-1251152 racemate - CAS# 1610358-53-6 0158 Pleiotropic effects of the sirtuin

SKU: 99786010735

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Description

Pleiotropic effects of the sirtuin inhibitor sirtinol involves concentration-dependent modulation of multiple nuclear receptor-mediated pathways in androgen-responsive prostate cancer cell LNCaP

and inhibits only 3 out of 70 nonkinase enzymes and receptors

Chemical Name: N -[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3

9(8):514-20

CAS Number: 2169266-69-5

BAY-1251152 racemate - CAS# 1610358-53-6 0158 Pleiotropic effects of the sirtuinBAY 1251152 racemate, CAS No. 1610358 53 6, also known as () BAY 1251152, is a racemic mixture of BAY 1251152. BAY 1251152 is a potent and highly selective PTEF CDK9 inhibitor. BAY 1251152 racemate, CAS No. 1610358 53 6, binds to and blocks the phosphorylation and kinase activity of CDK9, thereby preventing PTEFb mediated activation of RNA Pol II and leading to the inhibition of gene transcription of various anti apoptotic proteins. This may cause

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