INCA-6 Size:Contact [email protected] for quotation InChi: InChI=1S/C27H36N2O4/c1-4-33-25-17-20(12-13-22(25)27(31)32)18-26(30)28-23(16-19(2)3)21-10-6-7-11-24(21)29-14-8-5-9-15-29/h6-7

InChi: InChI=1S/C27H36N2O4/c1-4-33-25-17-20(12-13-22(25)27(31)32)18-26(30)28-23(16-19(2)3)21-10-6-7-11-24(21)29-14-8-5-9-15-29/h6-7

4 mg/kg)-treated animals exhibit ethopharmacological profiles characterized by a decrease in offensive behaviors without impairment of motor activity (0

CAS Number: 931417-26-4

2 minutes) without affecting the basal sIPSC frequency at the range of 10 pM to 1 nM

Valimaki MJ

INCA-6 Size:Contact [email protected] for quotation InChi: InChI=1S/C27H36N2O4/c1-4-33-25-17-20(12-13-22(25)27(31)32)18-26(30)28-23(16-19(2)3)21-10-6-7-11-24(21)29-14-8-5-9-15-29/h6-7INCA 6 is a selective inhibitor of transcription factor NFAT with Kd value of 0. 8 mM in vitro. NFAT (Nuclear factor of activated T cells) is a general name which is applied to a family of transcription factors that are important in immune response. They are expressed in most immune system cells. Calcium signaling plays an important role in NFAT activation. Calmodulin activates calcineurin (CN) which is a serine threonine phosphatase, then