gamma-secretase modulator 2 - CAS# 1093978-89-2 60075 2-dihydropyridin-3-yl)methyl]-6-{4-[(morpholin-4-yl)methyl]phenyl}-1H-indazole-4-carboxamide

2-dihydropyridin-3-yl)methyl]-6-{4-[(morpholin-4-yl)methyl]phenyl}-1H-indazole-4-carboxamide

and TNF-α

5(6):665-79

5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-9-(hydroxymethyl)-2

Protopine is found to be cytoprotective against oxidative stress-induced cell death in vitro

gamma-secretase modulator 2 - CAS# 1093978-89-2 60075 2-dihydropyridin-3-yl)methyl]-6-{4-[(morpholin-4-yl)methyl]phenyl}-1H-indazole-4-carboxamidegamma secretase modulator 2 is a potent and selective secretase modulator for treatment of Alzheimer's disease. secretase secretase modulator is modulation of the action of secretase so as to Selectively attenuate production of A(1 42) and hence find use in treatment or prevention of diseases associated with deposition of A in the brain. secretase modulator is usful in particular Alzheimers disease. Product information CAS Number: 1093978 89 2