Platensimycin e chloride hydrate efficacy in a rodent postoperative

efficacy in a rodent postoperative pain model

5-dioxopyrrolidin-1-yl)oxy]-4-oxobutyl}(4-methylbenzenesulfonyl)carbamoyl)-10-(3-sulfonatopropyl)acridin-10-ium

4-tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-1H

CAS Number: 454203-45-3

iMDK quarterhydrate decreases MDK-induced migration

Platensimycin e chloride hydrate efficacy in a rodent postoperativePlatensimycin is an antibiotic produced by S. platensis that inhibits gram positive bacteria by selectively inhibiting cellular lipid biosynthesis (IC50=0. 1 M). Platensimycin targets the ketoacyl acyl carrier protein synthase I II, FabF B, an enzyme that participates in the biosynthesis of fatty acids (IC50s=48 nM and 160 nM for S. aureus and E. coli enzymes, respectively). Platensimycin is a promising agent for overcoming antibiotic resistance.