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Succinyl phosphonate mezan (DMXAA) PubMed PMID: 24716857

SKU: 14853164962

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Description

PubMed PMID: 24716857

(2012) AACR Chicago

in vivo and in vitro

Formula: C11H6ClN3O6

14-triaza-5

Succinyl phosphonate mezan (DMXAA) PubMed PMID: 24716857Succinyl phosphonate is an ketoglutarate dehydrogenase (KGDHC) inhibitor, effective inhibits (KGDHC) in muscle, bacterial, brain, and cultured human fibroblasts. Succinyl phosphonate trisodium salt is an 2 oxoglutarate dehydrogenase (OGDH) inhibitor, impairs viability of cancer cells in a cell specific metabolism dependent manner. Succinyl phosphonate trisodium salt inhibits the glutamate induced ROS production in glutamate stimulated hippocampal

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