Ko 143 PEG4-NH2 hydrochloride prevents glomerular sclerosis in a

prevents glomerular sclerosis in a Thy1 nephritis model

and significant reduction of covalently closed circular DNA (cccDNA) in animal models

Chemical Name: 2-hydroxyethane-1-sulfonic acid

Molecular Weight: 748

A chemical switch for inhibitor-sensitive alleles of any protein kinase

Ko 143 PEG4-NH2 hydrochloride prevents glomerular sclerosis in aKo 143 is a potent and selective breast cancer resistance protein multidrug transporter (BCRP) inhibitor (EC90 = 26 nM). Ko 143 is a nontoxic analog of fungal toxin fumitremorgin C, is a potent inhibitor of ABCG2. Product information CAS Number: 461054 93 3 Molecular Weight: 469. 57 Formula: C26H35N3O5 Chemical Name: tert butyl 3 [(2S,5S,8S) 14 methoxy 2 (2 methylpropyl) 4,7 dioxo 3,6,17 triazatetracyclo[8. 7. 0. 0,. 0,]heptadeca 1(10),11(16),12,14