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Chemical Name: N-(2-{[(1R)-1-[3-(trifluoromethyl)phenyl]ethyl]amino}-1H-1
by in vitro binding experiments
PubMed Central PMCID: PMC2821710
3)9-7-12(16)10(8-11(9)15)14(4
CNV 1014802
Methsuximide Catalog No.:M22869-C Chemical Name: N-(2-{[(1R)-1-[3-(trifluoromethyl)phenyl]ethyl]amino}-1H-1Methsuximide (or methsuximide, methosuximide, Celontin) is a succinimide anticonvulsant medication that is pharmacologically converted to its active metabolite N desmethylmethosuximide, a channel blocker that targets low threshold calcium currents. Methsuximide effectively suppressed the initial clonic seizures induced by Metrazol in rats and mice. Methsuximide was capable of protecting mice from tonic extensor seizures to supramaximal electroshock .
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