Almonertinib hydrochloride Catalog No.:M17886-C CAS Number: 2310262-10-1

Name: Almonertinib hydrochloride Catalog No.:M17886-C CAS Number: 2310262-10-1
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SKU: 16801799104
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Description

CAS Number: 2310262-10-1

06 mM and Ki'=0

Formula: C16H22ClNO3

83(2):341-7

Formula: C12H7N3O2S

Almonertinib hydrochloride Catalog No.:M17886-C CAS Number: 2310262-10-1Almonertinib (HS 10296) hydrochloride is an orally available, irreversible, third generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR sensitizing and T790M resistance mutations. Almonertinib hydrochloride shows great inhibitory activity against T790M, T790M L858R and T790M Del19 (IC50: 0. 37, 0. 29 and 0. 21 nM, respectively), and is less effective against wild type (3. 39 nM). Almonertinib hydrochloride is used for the research

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