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The novel inhibitor PRI-724 for Wnt/β-catenin/CBP signaling ameliorates bleomycin-induced pulmonary fibrosis in mice
Formula: C26H35F3O6
Smiles: C[C@H](CC[C@@H](O)C1CC1)[C@H]1CC[C@H]2/C(/CCC[C@@]21C)=C/C=C1/C[C@@H](O)C[C@H](O)C/1=C
Molecular Weight: 871
InChiKey: YURJSTAIMNSZAE-HHNZYBFYSA-N
Carvedilol - CAS# 72956-09-3 famostat Hydrochloride The novel inhibitor PRI-724 forCarvedilol (free base) is a non selective beta adrenoceptor blocking agent (S( ) enantiomer) and as an alpha 1 adrenoceptor blocker (R(+) and S( ) enantiomers) indicated in the treatment of mild to moderate congestive heart failure (CHF). Its acts more strongly on beta receptors than on alpha 1 receptors, reduces peripheral vascular resistance by vasodilation, and prevents reflex tachycardia (beta blockade) so that heart rate is either unchanged or
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