Cyclosporin A-Derivative 1 Free base - CAS# 286852-20-8 Catalog No.:M15159-2 Smiles: C[C@@H]1O[C@@H](O[C@H]2[C@@H](O[C@H](CO)[C@@H](O)[C@@H]2O)OC2C=C3O[C@@H](CC(=O)C3=C(O)C=2)C2=CC(O)=C(O)C=C2)[C@H](O)[C@H](O)[C@H]1O

Smiles: C[C@@H]1O[C@@H](O[C@H]2[C@@H](O[C@H](CO)[C@@H](O)[C@@H]2O)OC2C=C3O[C@@H](CC(=O)C3=C(O)C=2)C2=CC(O)=C(O)C=C2)[C@H](O)[C@H](O)[C@H]1O

MDL-28170 (Calpain Inhibitor III) is a potent and selective calpain inhibitor of calpain that penetrates the blood-brain barrier and inhibits brain cysteine protease activity after systemic administration

05-1 µM concentration in a panel of in vitro assays

Formula: C75H75F9N4O19

PubMed Central PMCID: PMC2596241

Cyclosporin A-Derivative 1 Free base - CAS# 286852-20-8 Catalog No.:M15159-2 Smiles: C[C@@H]1O[C@@H](O[C@H]2[C@@H](O[C@H](CO)[C@@H](O)[C@@H]2O)OC2C=C3O[C@@H](CC(=O)C3=C(O)C=2)C2=CC(O)=C(O)C=C2)[C@H](O)[C@H](O)[C@H]1OCyclosporin A Derivative 1 (Free base) is a crystalline intermediate derived from the opening of cyclosporin A extracted from patent WO 2013167703 A1. Cyclosporin A is an immunosuppressive agent which can bind to the cyclophilin and inhibit calcineurin. Product information CAS Number: 286852 20 8 Molecular Weight: 1276. 69 Formula: C65H117N11O14 Chemical Name: methyl 2 [[(2S) 2 [[(E, 2S, 3R, 4R) 3 acetyloxy 4 methyl 2 [methyl [(2S) 3 methyl 2 [methyl