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Destruxin B - CAS# 2503-26-6 nelate CAS Number: 2752-65-0

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Description

CAS Number: 2752-65-0

Chemical Name: propan-2-yl (2Z)-3-{3-[3-methoxy-5-(trifluoromethyl)phenyl]-1H-1

9-trioxa-12-azatetradec-1-yl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide

thereby inhibiting tumor cell proliferation

SC-26196 inhibited the desaturation of 2 microM [1-14C] 18:2n-6 by 87-95% in cultured human skin fibroblasts

Destruxin B - CAS# 2503-26-6 nelate CAS Number: 2752-65-0Destruxin B, isolated from entomopathogenic fungus Metarhizium anisopliae, is one of the cyclodepsipeptides with insecticidal and anticancer activities. Destruxin B induces apoptosis via a Bcl 2 Family dependent mitochondrial pathway in human nonsmall cell lung cancer cells. Destruxin B significantly activates caspase 3 and reduces tumor cell proliferation through caspase mediated apoptosis, not only in vitro but also in vivo. Product information CAS

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