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5 μM to 0
InChiKey: UHVDWBQHXMQETH-UHFFFAOYSA-N
and Bcl-2 and down-regulate the expression of caspase-3
another agonist with predominant 5-HT2 actions
Formula: C11H14O4
EGFR-IN-1 14 mesylate 5 μM to 0EGFR IN 1 (compound 24) is an orally active and irreversible L858R T790M mutant selective EGFR inhibitor. EGFR IN 1 potently inhibits Gefitinib resistant EGFR L858R, T790M with 100 fold selectivity over wild type EGFR. EGFR IN 1 displays strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. Antitumor activity. Product information CAS Number: 1625677 63 5 Molecular Weight: 514. 58 Formula: C28H30N6O4 Chemical
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