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GSK650394 inhibits the growth of LNCaP cells with IC50 of approximately 1 μM
Formula: C14H11N
CAS Number: 71617-10-2
Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193
2-diphenylethyl)amino)propoxy)phenyl)acetic acid hydrochloride
K-7174 dihydrochloride iophen-2-yl)-2-(2-(m-tolyl)hydrazono)butane-1 3-dione GSK650394 inhibits the growth ofK 7174 is a novel orally active, potent proteasome inhibitor. K 7174 exerts anti myeloma activity in vitro and in vivo by down regulating the expression of class I histone deacetylases. K 7174 kills bortezomib resistant myeloma cells carrying a 5 subunit mutation in vivo and primary cells from a patient resistant to bortezomib. K 7174 is also a GATA specific inhibitor, which may have potential application in treating anemia of chronic disease. Product
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