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ETP-46321 Size:Solid 10 mg Donovan KA

SKU: 26099733752

4.1
USD115.00 USD148.00

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Description

Donovan KA

Antibacterial activity of tannins isolated from Sapium baccatum extract and use for control of tomato bacterial wilt

54(9):3641-50

5(5):357-70

Bay 11-7082 inhibits transcription factor NF-kappaB and induces apoptosis of HTLV-I-infected T-cell lines and primary adult T-cell leukemia cells

ETP-46321 Size:Solid 10 mg Donovan KAETP 46321 is a potent and orally bioavailable PI3K , inhibitor with potent biochemical and cellular activity and good pharmacokinetic properties (PK) after oral dosing. ETP 46321 PK PD studies showed time dependent downregulation of AKT(Ser473) phosphorylation, which correlates with compound levels in tumor tissue and demonstrating to be efficacious in a GEMM mouse tumor model driven by a K Ras(G12V) oncogenic mutation. Treatment with ETP 46321

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