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Mefloquine Hydrochloride - CAS# 51773-92-3 Size:Solid 10 mg is a potent and selective

SKU: 26101579010

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Description

is a potent and selective activator of mutant p53R175 (EC50 ~8 nM in mutant p53 cell lines but with >100-fold selectivity in wild type cells)

Exposures (AUC) increases in a less than dose-proportional manner from 23 μM•h at 5 mg/kg to 362 μM•h at 500 mg/kg

Ruiz de Almodovar C

Stranks EK

16-pentaazacycloicosane-3-carbonyl]pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-4-methylpentanamide

Mefloquine Hydrochloride - CAS# 51773-92-3 Size:Solid 10 mg is a potent and selectiveMefloquine hydrochloride is a phospholipid interacting antimalarial drug. It is very effective against plasmodium falciparum with very few side effects. When used for prevention it is taken once a week and should be begun one or two weeks before potential exposure and continued for four weeks after potential exposure. It can be used to treat mild or moderate malaria but should not be used to treat severe malaria. Product information CAS Number: 51773

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