JSH-150 15118 EGFR-IN-2 also shows good selectivity

EGFR-IN-2 also shows good selectivity against other kinases when evaluated in a 225-kinase panel (12/225 kinases inhibited at >70% when tested at 0

67 mg/mL (143

which interestingly preceeds changes in H3K4me2 levels

CGP55845 hydrochloride is a potent and selective GABAB receptor antagonist with an IC50 of 6 nM

1044870-39-4

JSH-150 15118 EGFR-IN-2 also shows good selectivityJSH 150 is a highly selective and potent CDK9 inhibitor with an IC50 of 1 nM. Product information CAS Number: 2247481 21 4 Molecular Weight: 505. 08 Formula: C24H33ClN6O2S Chemical Name: 4 ({[4 (5 chloro 2 {[(1r,4r) 4 [(2 methoxyethyl)amino]cyclohexyl]amino}pyridin 4 yl) 1,3 thiazol 2 yl]amino}methyl)oxane 4 carbonitrile Smiles: COCCN[C@@H]1CC[C@H](CC1)NC1C=C(C(Cl)=CN=1)C1=CSC(NCC2(CCOCC2)C#N)=N1 InChiKey: XSDZPPRQLIZLDG IYARVYRRSA N InChi: InChI=1S