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Lintitript produces concentration dependent inhibition of [125I]CCK binding to CCK1 receptor sites in the rat pancreas (IC50 value of 0
InChiKey: MWLKUSHZNSYRKK-HXUWFJFHSA-N
CAS Number: 943540-74-7
with anticancer activity
Chemical Name: (6S)-6-hydrogenio-8λ⁶-thia-2
SNX-5422 Mesylate (PF-04929113 (Mesylate)) Size:Contact [email protected] for quotation Lintitript produces concentration dependent inhibitionSNX 5422 Mesylate (PF 04929113 Mesylate), a prodrug of SNX 2112, is an orally active Hsp90 inhibitor, with a Kd of 41 nM, and also induces Her 2 degradation, with an IC50 of 37 nM. SNX 5422 is an orally active Hsp90 inhibitor, with a Kd of 41 nM, and also induces Her 2 degradation, with an IC50 of 37 nM. SNX 5422 exhibits potent effects on Her2 and p ERK stability in AU565 cells and p S6 in A375 cells, with IC50s of 5 1, 11 3, and 61 22 nM,
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