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CC(C)(C)C1=CC(NC(=O)NC2C=CC(=CC=2)C2=CN3C(=N2)SC2=CC(=CC=C32)OCCN2CCOCC2)=NO1
9(11):2471-8
Adrián FJ
Chemical Name: N1-((1R
a histone deacetylase inhibitor
BAZ2-ICR - BAZ2 Bromodomain Inhibitor. CAS# 1665195-94-7 size:2 mg solid CC(C)(C)C1=CC(NC(=O)NC2C=CC(=CC=2)C2=CN3C(=N2)SC2=CC(=CC=C32)OCCN2CCOCC2)=NO1BAZ2 ICR, CAS No. 1665195 94 7, is a potent and selective BAZ2 bromodomain inhibitor with Kd values of 109 and 170 nM for BAZ2A and BAZ2B, respectively. It exhibits 15 fold selectivity for the BAZ2 bromodomain over the CERC2 bromodomain and >100 fold selectivity over a range of other bromodomains. It shows accelerated FRAP recovery at 1 M in the BAZ2A FRAP assay. Product information CAS Number: 1665195 94 7 Molecular Weight: 357. 41 Formula: C20H19N7
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