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M-31850 produces a dose dependent increase in MUG hydrolysis (Hex S levels) in lysates from treated infantile Sandhoff disease (ISD) cells
Smiles: N[C@@H](CCSSCC[C@H](N)C(O)=O)C(O)=O
which built up rapidly and preferentially in cells with a dysfunctional TCA cycle
Chemical Name: (E)-(4-(2-(1H-indazol-3-yl)vinyl)phenyl)(piperazin-1-yl)methanone
angio-/lympho-genesis
Fibrinogen-Binding Peptide ido-PEG9-azide M-31850 produces a dose dependentFibrinogen Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen Binding Peptide binds fibrinogen and inhibits both the adhesion of platelets to fibrinogen and platelet aggregation, and also inhibits the adhesion of platelets to vitronectin. Product information CAS Number: 137235 80 4 Molecular Weight: 565. 62 Formula: C25H39N7O8 Chemical Name:
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