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with an IC(50) of 0
Istradefylline (KW-6002) is a selective antagonist at the A2A receptor
InChi: InChI=1S/C25H28N6O/c1-15-11-22(31-13-16(2)27-17(3)14-31)26-12-21(15)18-5-7-19(8-6-18)23-28-24-20(25(32)29-23)9-10-30(24)4/h5-12
Chemical Name: 2-nitro-5-tosylfuran
which inhibits the production of exocellular keratinase
KPT-9274 Size:Contact [email protected] for quotation with an IC(50) of 0KPT 9274 is a selective and orally bioavailable allosteric inhibitor of PAK4 . P21 protein (Cdc42 Rac) activated kinase 4 (PAK4) is a serine threonine protein kinase and a member of the PAK family of proteins which are Rac1 and Cdc42 effectors. PAK4 is a mediator of filopodia formation and stabilizes catenin transcriptional activity, and is involved in disease progression for several solid tumors . KPT 9274 is a selective and orally bioavailable PAK4
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