AC-4-130 Catalog No.:M31939-C InChi: InChI=1S/C25H30O4/c1-20(12-8-14-22(3)16-18-24(26)27)10-6-7-11-21(2)13-9-15-23(4)17-19-25(28)29-5/h6-19H

InChi: InChI=1S/C25H30O4/c1-20(12-8-14-22(3)16-18-24(26)27)10-6-7-11-21(2)13-9-15-23(4)17-19-25(28)29-5/h6-19H

Smiles: CCOC(=O)C(C)OC1=CC=CC2=C1C=CN(CC(=O)NC1=CC3OCCOC=3C=C1)C2=O

Chemical Name: {[(1S)-1-(chloromethyl)-3-(5-{5-[4-methyl-4-(methyldisulfanyl)pentanamido]-1H-indole-2-amido}-1H-indole-2-carbonyl)-1H

polycythemia vera

The VSIV G protein has also been used in cytological studies of trafficking in the endomembrane system

AC-4-130 Catalog No.:M31939-C InChi: InChI=1S/C25H30O4/c1-20(12-8-14-22(3)16-18-24(26)27)10-6-7-11-21(2)13-9-15-23(4)17-19-25(28)29-5/h6-19HAC 4 130 is a potent STAT5 SH2 domain inhibitor. AC 4 130 directly binds to STAT5 and disrupts STAT5 activation, dimerization, nuclear translocation, and STAT5 dependent gene transcription. AC 4 130 induces cell cycle arrest and apoptosis in FLT3 ITD driven leukemic cells. AC 4 130 has anti cancer activity and can efficiently block pathological levels of STAT5 activity in acute myeloid leukemia (AML). Product information CAS Number: 1834571 82 2