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PubMed PMID: 24488306
Smiles: OC1C(I)=C(C(I)=CC=1I)C(O)=O
Williams D
with an IC50 of 82 nM
229(10):1455-65
Phthalimide-PEG3-C2-OTs Catalog No.:M14332-2 PubMed PMID: 24488306Phthalimide PEG3 C2 OTs (Compound 5) is a PROTAC linker, which refers to the PEGs composition. Phthalimide PEG3 C2 OTs can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin proteasome system to selectively degrade target proteins. Product information CAS Number:
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