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Freselestat (ONO-6818
85% NaCl solution immediately prior to use
20-50 mg/kg/day of IP or 25-100 mg/kg/day of PO
except 5-HT3 with Ki of 930 nM
SB228357 has antidepressant/anxiolytic effects
MK6-83 rimethoprim-d3 Freselestat (ONO-6818MK6 83 is a new candidate agonist of TRPML1 with an improved efficacy and potency. MK6 83 has the potential for Mucolipidosis type IV study. Product information CAS Number: 1062271 24 2 Molecular Weight: 336. 47 Formula: C16H20N2O2S2 Chemical Name: 5 methyl N [2 (piperidin 1 yl)phenyl]thiophene 2 sulfonamide Smiles: CC1=CC=C(S1)S(=O)(=O)NC1=CC=CC=C1N1CCCCC1 InChiKey: IRGYSXZCDAWOOC UHFFFAOYSA N InChi: InChI=1S C16H20N2O2S2 c1 13 9 10 16(21