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PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4
InChiKey: ISBSSBGEYIBVTO-RCXKVKFCSA-N
InChi: InChI=1S/C21H20NO6
InChi: InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8
Oroxin B selectively induces tumor-suppressive ER stress and concurrently inhibits tumor-adaptive ER stress in B-lymphoma cells for effective anti-lymphoma therapy
Imatinib hydrochloride in fumarate PROTAC 1 is a partialDescription: IC50 Value: 100 nM (PDGFR) ; 100 nM (c Kit) Imatinib is a multi target inhibitor of v Abl, c Kit and PDGFR with IC50 of 0. 6 M, 0. 1 M and 0. 1 M, respectively. Imatinib is used to treat chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GISTs) and a number of other malignancies. in vitro: In vitro assays for inhibition of a panel of tyrosine and serine threonine protein kinases show that Imatinib inhibits the v Abl
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