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CN1CCN(CCC1)C1N=C2C=C(OC)C(=CC2=C(NC2CCN(CC3C=CC=CC=3)CC2)N=1)OC
478688-75-4 (trans&cis)
HBX41108 was used at 10 µM final concentration in various in vitro assays
and SMARCA2 even at 10 μM
1419949-20-4
RN-1 - LSD1 Inhibitor. CAS# 1781835-13-9 size:10mg solid CN1CCN(CCC1)C1N=C2C=C(OC)C(=CC2=C(NC2CCN(CC3C=CC=CC=3)CC2)N=1)OCRN 1, CAS No. 1781835 13 9, is a potent, specific and brain penetrant Lysine Specific Demethylase 1 (LSD1) inhibitor. RN 1 inhibits LSD1 in biochemical assay with an IC50 ~70 nM, and has weaker activity against monoamine oxidase proteins MAO A and MAO B with IC50 ~0. 51 M and 2. 79 M respectively. It exhibits good brain penetration and retention following systemic administration. RN 1 can abolish long term memory formation without affecting short term
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