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135(5):1669-72
which are required for MLL1 mediated leukemogenesis
but reduces open probability by > 90% with Ki=0
GNF7156 was orally dosed to mice at 50 mg/kg twice a day for 14 days
CX-4945 (Silmitasertib)
FH1 - Hepatocytes Functional Enhancer. CAS# 2719-05-3 090 135(5):1669-72FH1, CAS No. 2719 05 3, is a potent and selective small molecule that enhances hepatocyte functions and promotes the differentiation and maturation of iPSC derived hepatocytes toward a more mature phenotype in vitro. FH1 was identified by a high throughput, cell based screening using primary human hepatocytes. It was added to the basal medium with or without OSM on day 21 after the initiation of differentiation of iPSCs and acted over a period of 9