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Osimertinib dimesylate 0-anthracenedione is orally available cyclin-dependent kinase

SKU: 31549707499

4.8
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Description

is orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway

Sulforaphane inhibits the reinitiation of growth and diminishes cellular viability in quiescent colon carcinoma cells (HT29) and has a lower toxicity on differentiated CaCo2 cells

reducing excitatory transmission

Smiles: CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CCC4=C/C(/CC[C@]4(C)[C@H]3CC[C@]12C)=N\O

Hamouda AK

Osimertinib dimesylate 0-anthracenedione is orally available cyclin-dependent kinaseOsimertinib dimesylate (AZD 9291 dimesylate) is an irreversible and mutant selective EGFR inhibitor with IC50s of 12 and 1 nM against EGFRL858R and EGFRL858R T790M, respectively. Product information CAS Number: 2070014 82 1 Molecular Weight: 691. 82 Formula: C30H41N7O8S2 Chemical Name: N (2 {[2 (dimethylamino)ethyl](methyl)amino} 4 methoxy 5 {[4 (1 methyl 1H indol 3 yl)pyrimidin 2 yl]amino}phenyl)prop 2 enamide; bis(methanesulfonic acid) Smiles:

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