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MY-5445 Size:2mg solid InChi: InChI=1S/C25H23Cl2FN6O/c1-2-34-23-15(11-19(24(34)35)18-5-3-16(26)12-20(18)27)14-30-25(32-23)31-17-4-6-22(21(28)13-17)33-9-7-29-8-10-33/h3-6

SKU: 32171787664

4.4
USD168.00 USD197.00

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Description

InChi: InChI=1S/C25H23Cl2FN6O/c1-2-34-23-15(11-19(24(34)35)18-5-3-16(26)12-20(18)27)14-30-25(32-23)31-17-4-6-22(21(28)13-17)33-9-7-29-8-10-33/h3-6

InChiKey: BTYHAFSDANBVMJ-UHFFFAOYSA-N

The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

Smiles: CN1CCN(CC1)C1=CC(=CC=C1)NC1=NN2C=CC=C(C2=N1)C1C=CC(=CC=1)S(C)(=O)=O

In vitro activity and resistance profile of dasabuvir

MY-5445 Size:2mg solid InChi: InChI=1S/C25H23Cl2FN6O/c1-2-34-23-15(11-19(24(34)35)18-5-3-16(26)12-20(18)27)14-30-25(32-23)31-17-4-6-22(21(28)13-17)33-9-7-29-8-10-33/h3-6MY 5445 is a specific inhibitor of the cyclic GMP phosphodiesterase, phosphodiesterase type 5 (PDE5), with a Ki of 1. 3 M. MY 5445 inhibits human platelet aggregation. MY 5445 is a selective modulator of ATP binding cassette (ABC) transporter ABCG2, with anti proliferative effect. Product information CAS Number: 78351 75 4 Molecular Weight: 331. 80 Formula: C20H14ClN3 Chemical Name: N (3 chlorophenyl) 4 phenylphthalazin 1 amine Smiles:

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