RO-5963 - CAS# 1416663-77-8 azono)butane-1 3-dione CAS Number: 956590-23-1

CAS Number: 956590-23-1

Propylparaben inhibits mouse cultured antral follicle growth

Smiles: C[N+]1C=CN(C[C@@]2(C)[C@H](C([O-])=O)N3[C@@H](CC3=O)S2(=O)=O)N=1

Smiles: CC1(C)[C@@H]2[C@H](C[C@]3(C)[C@H](C[C@@H](O)[C@@H]4[C@H](CC[C@@]34C)[C@](C)(CCC=C(C)C)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@]2(C)CC[C@@H]1O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O[C@@H]1OC[C@@H](O)[C@H](O)[C@H]1O

and is approximately 135-fold more potent than imatinib for inhibiting the PDGFRA D842V mutation

RO-5963 - CAS# 1416663-77-8 azono)butane-1 3-dione CAS Number: 956590-23-1RO 5963 is a dual p53 MDM2 and p53 MDMX inhibitor with IC50s of ~17 nM and ~24 nM, respectively. Product information CAS Number: 1416663 77 8 Molecular Weight: 518. 90 Formula: C24H21ClF2N4O5 Chemical Name: 2 [(4E) 4 [(6 chloro 7 methyl 1H indol 3 yl)methylidene] 2, 5 dioxoimidazolidin 1 yl] 2 (3, 4 difluorophenyl) N (1, 3 dihydroxypropan 2 yl)acetamide Smiles: CC1=C(Cl)C=CC2=C1NC=C2 C=C1 NC(=O)N(C(C2=CC(F)=C(F)C=C2)C(=O)NC(CO)CO)C 1=O InChiKey: