Itacitinib adipate 683ZT triphosphate TEA(x) which inhibits degranulation downstream of

which inhibits degranulation downstream of protein kinase C activation or Ca2+ influx from an internal store in RBL-213 cells

3-dihydroxypropylidene]amino]-1-hydroxy-4-methylpentylidene]amino]-1-hydroxypropylidene]amino]propanoyl]pyrrolidin-2-yl](hydroxy)methylidene}amino]-N-[(1S)-4-carbamimidamido-1-[(Z)-[(1S)-1-(C-hydroxycarbonimidoyl)-2-phenylethyl]-C-hydroxycarbonimidoyl]butyl]pentanediimidic acid

InChi: InChI=1S/C29H35N7O3

eprod Biol Endocrinol

CAS Number: 187870-95-7

Itacitinib adipate 683ZT triphosphate TEA(x) which inhibits degranulation downstream ofItacitinib adipate is an orally bioavailable and selective JAK1 inhibitor which has been tested for efficacy and safety in a phase II trial in myelofibrosis. Product information CAS Number: 1334302 63 4 Molecular Weight: 699. 66 Formula: C32H33F4N9O5 Chemical Name: 2 (1 {1 [3 fluoro 2 (trifluoromethyl)pyridine 4 carbonyl]piperidin 4 yl} 3 (4 {7H pyrrolo[2,3 d]pyrimidin 4 yl} 1H pyrazol 1 yl)azetidin 3 yl)acetonitrile; hexanedioic acid Smiles: