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It induces G2/M phase arrest in CNE-2 cells
21)/t17-/m0/s1
InChiKey: MXJWRABVEGLYDG-UHFFFAOYSA-N
and exhibits anti-tumor activity in multiple xenograft models carrying mutations in BRaf
Formula: C13H20N4O3
Phenoxodiol - CAS# 81267-65-4 Size:10mg solid It induces G2/M phase arrestPhenoxodiol, a synthetic analog of Genestein, activates the mitochondrial caspase system, inhibits XIAP (an apoptosis inhibitor), and sensitizes the cancer cells to Fas mediated apoptosis. This agent also inhibits DNA topoisomerase II by stabilizing the cleavable complex. Phenoxodiol induces cell cycle arrest in the G1 S phase of the cell cycle and upregulates p21WAF1 via a p53 independent manner. Product information CAS Number: 81267 65 4 Molecular
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