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Tamibarotene - CAS# 94497-51-5 Catalog No.:M10640-10 WDR5-0103 was used at 10

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Description

WDR5-0103 was used at 10 µM final concentration in various in vitro assays

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Tamibarotene - CAS# 94497-51-5 Catalog No.:M10640-10 WDR5-0103 was used at 10Tamibarotene, also known as SY 1425, is an orally active, synthetic retinoid, developed to overcome all trans retinoic acid (ATRA) resistance, with potential antineoplastic activity. As a specific retinoic acid receptor (RAR) alpha beta agonist, tamibarotene is approximately ten times more potent than ATRA in inducing cell differentiation and apoptosis in HL 60 (human promyelocytic leukemia) cell lines in vitro. Due to a lower affinity for cellular

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