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Salinomycin has been shown by Piyush Gupta et al
tumor growth inhibition increases with increased exposure of the compound and that tumor regressions could only be achieved when the compound exposure consistently exceeded 90% of c-MET inhibition
PubMed PMID: 25337060
It was identified by an imaging-based high throughput screening in human MSCs
Duvelisib for CLL/SLL and follicular non-Hodgkin lymphoma
A66 - CAS# 1166227-08-2 Catalog No.:M7134-10 Salinomycin has been shown byA66, CAS No. 1166227 08 2, is a potent and highly selective p110 inhibitor with IC50 of 32 nM in a cell free assay, >100 fold selectivity for p110 over other class I PI3K isoforms. A66 blocks phosphoinositide 3 kinase signalling and tumour growth in certain cell types. Product information CAS Number: 1166227 08 2 Molecular Weight: 393. 53 Formula: C17H23N5O2S2 Synonym: A66 A 66 A 66 Chemical Name: (S) N1 (2 (tert butyl) 4' methyl [4,5' bithiazol] 2'